Study of Electroencephalogram (EEG) Measurement During Different Stimulations of the Lower Urinary Tract

Not Applicable

Completed

• Conditions: Nonneurogenic Neurogenic Bladder Dysfunction; Neurogenic Bladder Dysfunction Nos; Healthy
• Interventions: Other: Electroencephalography

• Registration Number: NCT01389921
• Lead Sponsor: Ulrich Mehnert

Brief Summary

The purpose of this study is to investigate afferent and cortical activities during bladder filling under different stimulations of the lower urinary tract. The participants of the study are healthy test persons and patients with overactive bladder.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-02
• Study First Submitted: 2011-06-28
• Study First Submitted QC: 2011-07-07
• Study First Posted: 2011-07-08
• Primary Completion: 2011-09
• Study Completion: 2014-04
• Status Verified: 2019-07
• Last Update Submitted: 2019-07-19
• Last Update Posted: 2019-07-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 83

Inclusion Criteria

• Right-handed
• Written informed consent

Exclusion Criteria

• Any psychological diseases
• Any renal, cardiac, and pulmonary diseases
• Pregnancy or breastfeeding
• Problems keeping calm for 60 minutes in the sitting position
• Medication influencing EEG or bladder function

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
patients with non-neurogenic OAB	Electroencephalography	Electroencephalography recording during electrical stimulation of different locations of the lower urinary tract as well as during electrical and heat stimulation at the tibial and pudendal nerve and S3 dermatome.
healthy testpersons	Electroencephalography	Electroencephalography recording during electrical stimulation of different locations of the lower urinary tract as well as during electrical and heat stimulation at the tibial and pudendal nerve and S3 dermatome.
patients with neurogenic OAB	Electroencephalography	Electroencephalography recording during electrical stimulation of different locations of the lower urinary tract as well as during electrical and heat stimulation at the tibial and pudendal nerve and S3 dermatome

Primary Outcome Measures

Name	Time	Method
Establishment of somatosensory evoked potentials of lower urinary tract stimulations	3 times on an average period of three months	EEG recording during electrical stimulation of different locations of the lower urinary tract as well as during electrical and heat stimulation at the tibial and pudendal nerve and S3 dermatome.

Trial Locations

Locations (1)

Spinal Cord Injury & Research, University of Zürich, Balgrist University Hospital; 🇨🇭 Zürich, Switzerland