Investigation of Lower Urinary Tract Afferent and Cortical Brain Activity During Lower Urinary Tract Stimulation Using Electroencephalogram Measurements
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 83
- 试验地点
- 2
- 主要终点
- Establishment of somatosensory evoked potentials of lower urinary tract stimulations
研究概览
简要总结
The purpose of this study is to investigate afferent and cortical activities during bladder filling under different stimulations of the lower urinary tract. The participants of the study are healthy test persons and patients with overactive bladder.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Right-handed
- •Written informed consent
排除标准
- •Any psychological diseases
- •Any renal, cardiac, and pulmonary diseases
- •Pregnancy or breastfeeding
- •Problems keeping calm for 60 minutes in the sitting position
- •Medication influencing EEG or bladder function
研究组 & 干预措施
healthy testpersons
Electroencephalography recording during electrical stimulation of different locations of the lower urinary tract as well as during electrical and heat stimulation at the tibial and pudendal nerve and S3 dermatome.
干预措施: Electroencephalography (Other)
patients with non-neurogenic OAB
Electroencephalography recording during electrical stimulation of different locations of the lower urinary tract as well as during electrical and heat stimulation at the tibial and pudendal nerve and S3 dermatome.
干预措施: Electroencephalography (Other)
patients with neurogenic OAB
Electroencephalography recording during electrical stimulation of different locations of the lower urinary tract as well as during electrical and heat stimulation at the tibial and pudendal nerve and S3 dermatome
干预措施: Electroencephalography (Other)
结局指标
主要结局
Establishment of somatosensory evoked potentials of lower urinary tract stimulations
时间窗: 3 times on an average period of three months
EEG recording during electrical stimulation of different locations of the lower urinary tract as well as during electrical and heat stimulation at the tibial and pudendal nerve and S3 dermatome.
次要结局
未报告次要终点
研究者
Ulrich Mehnert
Executive physician
University of Zurich