The Impacts of the Different Anesthesia Methods on Patients of Transbronchial Cryobiopsy

Not Applicable

• Conditions: Transbronchial Cryobiopsy; Anesthesia; Tracheal Intubation; Rigid Bronchoscopy; Safety

• Registration Number: NCT04099069
• Lead Sponsor: Guangzhou Institute of Respiratory Disease

Brief Summary

to evaluate the difference between the tracheal intubation (TI) and rigid bronchoscopy (RB) under general anesthesia on patients with transbronchial cryobiopsy.

Detailed Description

To evaluate the difference between the tracheal intubation (TI) and rigid bronchoscopy (RB) under general anesthesia on patients with transbronchial cryobiopsy. Comparing the difference between two groups in the operating duration, extubation duration, total anesthesia time, heart rate, blood pressure and arterial blood gas analysis. This is a prospective, randomized, controlled trial.

Study Timeline

• Study First Submitted: 2019-05-28
• Status Verified: 2019-09
• Study First Submitted QC: 2019-09-19
• Last Update Submitted: 2019-09-19
• Study First Posted: 2019-09-23
• Last Update Posted: 2019-09-23
• Study Start: 2019-10-01
• Primary Completion: 2020-06-01
• Study Completion: 2020-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. The patients are admitted in the institution as ILD, while undefined after thorough history collection, laboratory examination and radiological data.
2. Transbronchial cryobiopsy(TBCB) is indicated by clinicians for definitive diagnosis and patients are content with the examination with agreement signed.
3. Blood gas analysis, routine blood test, ECG examination, coagulation function, immunological examination, chest HRCT, and liver/kidney function test have been completed

Exclusion Criteria

1. The radiological data indicates non-ILD
2. The clinical examinations mentioned above are not completed.
3. The patient cannot endure or does not agree the procedure.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
the fluctuation of blood pressure	24 hours	the fluctuation of blood pressure during the procedure
the fluctuation of heart rate	24 hours	fluctuation of heart rate during the procedure
the fluctuation of arterial partial pressure of carbon dioxide	24 hours	the fluctuation of arterial partial pressure of carbon dioxide during the procedure

Trial Locations

Locations (1)

The first affilliated hospital of Guanghzhou Medical university; 🇨🇳 Guangzhou, 广东, China