Comparison Effectiveness of Topical Analgesics without and with Entonox® during EsophagoGastroDuodenoscopy

Not Applicable

• Conditions: patients undergoing elective esophago- gastro- duodenoscopy (EGD) at the Siriraj Gastro- Intestinal Endoscopy Center. Inclusion criteria are patients aged between 18 and 70, American Society of Anesthesi; pain relief, inhalational route, oxygen/nitrous oxide gas mixture, Entonox®

• Registration Number: TCTR20200721001
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-21
• Study Completion: 2022-03-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 212

Inclusion Criteria

Patients aged between 18 and 70
Patients undergoing elective EGD
Patients undergoing topical anesthesia for EGD
American Society of Anesthesiologist (ASA) physical status class I/II
Able to complete questionnaires

Exclusion Criteria

Patients undergoing general anesthesia or TIVA for EGD
Patients at risk of aspiration such full stomach, gut obstruction, GI bleeding, achalasia, hiatal hernia
Allergy to lidocaine
Patients with head injuries
Maxillo-facial injuries
History of eye/ ear/nose/throat surgery in 6 months ago
Drunk/intoxicated patients
Severe COPD/asthma
Previous pneumothorax
Pregnancy
History of allergic to study drugs
Severe systemic medical diseases
BMI > 35 kg/m2

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison Effectiveness of Topical Analgesics without Entonox® and with Entonox® during Esophago- While insert endoscope 5-point Bath Gastroscopy Toleration Score (GTS)

Secondary Outcome Measures

Name	Time	Method
Evaluate the satisfaction of endoscopists Evaluate the satisfaction of patients Evaluate the si after endoscopic procedure and before discharge Numerical Rating Scale (NRS)