A pilot study to investigate the effects of one week of treatment with acetazolamide on the arterial levels of carbon dioxide in patients receiving non-invasive ventilation for the treatment of obesity hypoventilation syndrome

Not Applicable

• Conditions: Obesity hypoventilation syndrome; Respiratory - Other respiratory disorders / diseases; Diet and Nutrition - Obesity

• Registration Number: ACTRN12613000895785
• Lead Sponsor: niversity of Otago, Wellington

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-08-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Diagnosis of obesity hypoventilation syndrome
Currently receiving non-invasive ventilation in s-mode
No hospitalisation with decompensation of respiratory failure for at least 3 months
Willing and able to give informed consent

Exclusion Criteria

Unable to provide informed consent
Poor renal function (eGFR <30ml/min)
Poor compliance with non-invasive ventilation (average usage less than 4 hours per night)
Allergy or previous adverse reaction to sulphur drugs
Use of supplemental oxygen
Any other safety concern at investigators discression

Study & Design

• Study Type: Interventional
• Study Design: Not specified