Evaluation of eye disorder induced by chemotherapy including S-1
Not Applicable
- Conditions
- Gastrointestinal cancer
- Registration Number
- JPRN-UMIN000027192
- Lead Sponsor
- Hokkaido Gastrointestinal Cancer Study Group: HGCSG
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
Not provided
Exclusion Criteria
1) Prior medication of S-1. 2) Continuing the eye drops treatment. 3) Scheduled to have an ophthalmic operation within six months. 4) Lachrymal duct obstruction or more than three points of corner conjunctiva epithelium disorder score.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cumulative incidence of epiphora in periods from start of S-1 chemotherapy to 12 weeks after induction S-1
- Secondary Outcome Measures
Name Time Method cumulative incidence of epiphora in overall S-1 chemotherapy periods, the time of outbreak and severity of epiphora, the situation of ophthalmological intervention, ophthalmological changes, risk factors of epiphora, and QO