Randomised controlled trial to test the impact of increased consumption of wholegrain foods on cardiovascular disease (CVD) risk
- Conditions
- /A - this study looks at pre-disease/condition stateNot Applicable
- Registration Number
- ISRCTN83078872
- Lead Sponsor
- Food Standards Agency (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 300
Men and women, aged 30-65 years and with a body mass index (BMI) >25 kg/m^2
Volunteers for the study will be excluded if they are:
1. Habitual consumers of wholegrain cereals and wholegrain bread
2. Individuals receiving clinical treatment for Type 2 diabetes, hyperlipidaemia or hypertension
3. Currently prescribed non-steroidal anti-inflammatory drugs (NSAIDS), aspirin, steroids or immunosuppressants
4. Allergic or intolerant to intervention foods
5. Planning to change dietary habits, increase physical activity, change body weight, move away from the study centre-locality or take a lengthy vacation during the time of the study
6. Heavy smokers (>20 cigarettes per day)
7. Individuals with a history of substance abuse or alcoholism
8. Currently planning pregnancy or have had a baby in the past 12 months
9. Individuals who have shown a recent weight change (>2 kg in past 1 month)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ow-density lipoprotein (LDL) cholesterol
- Secondary Outcome Measures
Name Time Method