Interoceptive fear conditioning by using interoceptive stimuli and CO2 enriched air in healthy participants.
Recruiting
- Conditions
- Panic disorder10002861
- Registration Number
- NL-OMON34392
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 84
Inclusion Criteria
A good physical condition and age between 18-65 years
Exclusion Criteria
A psychiatric disorder- history of pulmonary disease (including asthma and lung fibrosis)- history of cardiovascular disease (including cardiac failure, suspicion of infarct, cardiomyopathy, TIA, angina pectoris, arrythmias)- hypertension- personal or familial history of cerebral aneurysm- pregnancy- epilepsy- psychotropic medication use- use of a2- or β-blockers- idiosyncratic response to pentagastrin- if participants refuse insight in deviant findings.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study outcome are the subjective reports of fear (VAS-F) during the<br /><br>test-phase. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary outcomes are the self reports of physical symptoms and the<br /><br>physiological measurements (respiration rate, tidal volume) that are assessed<br /><br>during the test-phase.</p><br>