NCT02835573Unknown不适用
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2016年4月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Diagnostic value of microRNAs evaluate by qPCR in patients of sepsis-induced myocardial injury
研究概览
简要总结
The purpose of this study is to evaluate the potential diagnostic and prognosis value of circulating microRNAs compared with cTnI for the patients of sepsis-induced myocardial injury at the emergency department (ED) and intensive care unit (ICU).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosis of sepsis:SOFA score increase >=2 at baseline level induced by infection.
- •Suspected myocardial injury,including 1 as follows at least:Low blood pressure or using vasoactive drugs; ECG changes(ST segment changes or pathological Q wave); Troponin elevation(> 0.5 μg/L); BNP elevation(> 4670pg/ml); Echocardiography: cardiac function decline(EF<50%).
排除标准
- •Skeletal muscle damage (induced by orthopedics, vascular surgery or trauma surgical disease, surgery);
- •Pregnant and lactating women;
- •Patients with mental disorders;
- •Patients are using other experimental drugs;
- •Refusal to provide informed consent
结局指标
主要结局
Diagnostic value of microRNAs evaluate by qPCR in patients of sepsis-induced myocardial injury
时间窗: Day 7
次要结局
- Prognostic value of microRNAs in patients of sepsis-induced myocardial injury(6 months)
研究者
Bin He
M.D./Ph.D.
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
研究点 (1)
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