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Prospective, randomized, open label trial of six vs. twelve months dual antiplatelet therapy after drug-eluting stent implantation in ST-elevation myocardial infarction.

Phase 4
Completed
Conditions
DAPT treatment after PCI
Dual-antiplatelettherapy after stent implantation
10011082
Registration Number
NL-OMON39800
Lead Sponsor
Maasstadziekenhuis
Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
580
Inclusion Criteria

STEMI patients between 18-85 years, who underwent PCI with second generation DES implantation

Exclusion Criteria

Key Exclusion Criteria Enrollment: Intolerance to Aspirin, Plasugrel, Ticagrelor, Heparin, Bivaluridin, Everoliumus or Zotarolimus.
Known bleeding diathesis or known coagulopathy.
Planned elective surgical procedure necessitating interruption of dual antiplatelet therapy during the first 6 months after randomization.;Key Exclusion Criteria Randomization:
Occurrence of death, myocardial infarction, stent thrombosis and target vessel or lesion revascularization during the first 6 months after inclusion.
Stroke or bleeding requiring discontinuation of DAPT during the first 6 months after inclusion.
Oral anticoagulant therapy with coumarin derivates.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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