The Risk of Uncomplicated Peptic Ulcer in a Cohort of Secondary Prevention Aspirin Users
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 39,000
- 试验地点
- 1
- 主要终点
- Incidence rates of uncomplicated peptic ulcer in a cohort of secondary prevention aspirin users
研究概览
简要总结
This study is conducted in a cohort of low dose aspirin (ASA) users previously ascertained. The aims of the post hoc analyses are:
To estimate the incidence of uncomplicated peptic ulcer (UPU) in a cohort of low-dose ASA for secondary prevention of vascular disease and the relative risk of UPU associated with use and discontinuation of use of low dose ASA.
To estimate the effect of proton pump inhibitors (PPI) on the occurrence of UPU among users of low-dose ASA for secondary prevention of vascular disease To evaluate the effect of other risk factors on the occurrence of UPU among users of low-dose ASA for secondary prevention of vascular disease.
详细描述
The risk of uncomplicated peptic ulcer in a cohort of secondary prevention aspirin users
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 50 Years 至 84 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 50-84 years in 2000-2007 with a first prescription of low dose ASA ( see study population description)
排除标准
- •Patients aged below age 50 and 85 years and above ( see study population description)
结局指标
主要结局
Incidence rates of uncomplicated peptic ulcer in a cohort of secondary prevention aspirin users
时间窗: From 1 January 2000 till 30 September 2011, an expected average of 6 years.
Risk (hazard ratio) of developing uncomplicated peptic ulcer in a cohort of secondary prevention aspirin users
时间窗: From 1 Januart 2000 till 30 September 2011, an expected average of 6 years
次要结局
未报告次要终点