Prevalence and predicting factors of significant liver fibrosis in chronic hepatitis B aged 40 years or more
Completed
- Conditions
- Prevalence and predicting factors of significant liver fibrosis evaluated by transient elastography in patients with chronic hepatitis B aged 40 years or more.Chronic hepatitis B, liver fibrosis, aged 40 years or more, prevalence, predicting factors
- Registration Number
- TCTR20220126005
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
1. Patients with chronic hepatitis B with age 40 years or more
2. No evidence of decompensated cirrhosis
3. Transient elastography is performed before anti-viral drugs intimidation or within 1 months after initiation
4. Transient elastography is performed by qualified physicians and its result is qualified.
Exclusion Criteria
1. No evidence of hepatocellular carcinoma or cholangiocarcinoma
2. ALT > 5 times of upper limit normal
3. Conditions affecting liver stiffness results e.g. heart failure, ascites, ESRD, cholestasis
4. Pregnancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence At time performing transient elastography Number of significant fibrosis patients/Number of overall patients
- Secondary Outcome Measures
Name Time Method Predicting factors of significant liver fibrosis At the end of study Multi variable logistic regression analysis