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The effect of tranexamic acid on perioperative bleeding in patients undergoing total knee or hip arthroplasty

Not Applicable
Conditions
osteoarthritis of knee or hip
Registration Number
JPRN-UMIN000036687
Lead Sponsor
Akita University
Brief Summary

A total of 135 patients were included during the study period. 63 patients for the control group and 72 patients for the TXA group. The demographic data were similar between the two groups. The intraoperative infusion, the postoperative transfusion, delta Hb, and estimated blood loss were significantly reduced in the TXA group, although there were no significant differences in the volumes of intraoperative transfusion and blood loss.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
135
Inclusion Criteria

Not provided

Exclusion Criteria

deep vein embolism pulmonary embolism

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
amount of intraoperative blood loss, intraoperative infusion volume, intraoperative blood transfusion volume, postoperative blood transfusion volume, the changes of hemoglobin concentrations , and estimated blood loss.
Secondary Outcome Measures
NameTimeMethod
pulmonary embolism, deep vein thrombosis
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