DECREASE-XIII: A randomized study of perioperative esmolol infusion for haemodynamic stability during major vascular surgery.

Suspended

• Conditions: atherosclerosis, vascular surgery, esmolol, cardiac complications

• Registration Number: NL-OMON20345
• Lead Sponsor: Erasmus Medical Centre, Rotterdam, The Netherlands

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Suspended
• Sex: Not specified
• Target Recruitment: 260

Inclusion Criteria

Adult patient undergoing elective major vascular surgery.

Exclusion Criteria

1. Bleeding;

2. Unstable cardiac conditions;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time with a heart rate outside the 60-80 BPM target window during the study drug infusion period.

Secondary Outcome Measures

Name	Time	Method
1. The occurence of cardiac death and myocardial ischemia;<br /><br>2. Safety parameters such as bradycardia, hypotension, TIA/Stroke.