Impact of Behavioral Factors on Treatment Adherence in a Sample of Rheumatoid Arthritis Patients
- Conditions
- Arthritis, Rheumatoid
- Interventions
- Behavioral: Questionnaire
- Registration Number
- NCT03754855
- Lead Sponsor
- University Hospital, Bordeaux
- Brief Summary
Rheumatoid arthritis (RA) care has been revolutionized in the last decade with the advent of biotherapies. Only 66% of treated patients are compliant. Nevertheless, studies analyzing the medication adherence in RA are rare. The aim of this study is thus to evaluate RA treatment adherence considering demographic data, vaccination coverage, feeding behavior and the use of e-health tools.
- Detailed Description
Rheumatoid arthritis (RA) care has been revolutionized in the last decade with the advent of biotherapies. The success of this therapeutic strategy is based on several factors, including the medication adherence. Whatever the method used, adherence evaluation is not sufficient, around 66% of the treated patients. Nevertheless, studies analysing the predictive factors of medication adherence in RA are rare.
RA patients are also educated about the infectious risk related to RA and treatments, and the importance of vaccination. These recommendations are not always respected by the patients, without knowing the exact factors leading to this decision. Furthermore, a lot of patients take personal initiatives without the agreement and the help of their practitioner, like diets or special feeding behaviors. Lastly, plenty of patients affected bv chronic diseases claim and use electronic health tools without any real evidence of the efficacy of such device.
The aim of this study is thus to evaluate RA treatment adherence considering demographic data, vaccination coverage, feeding behavior and the use of e-health tools.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 590
- patient aged over 18 years old,
- affected by RA according to ACR/EULAR 2010 criteria,
- francophone,
- and informed about the aims of the study.
- guardianship patient,
- patient who refuses to participate.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Rheumatoid Arthritis patients Questionnaire patients affected by RA according to ACR/EULAR 2010 criteria
- Primary Outcome Measures
Name Time Method Proportion of patients who presented a good medication adherence according to the medication adherence questionnaire At baseline (day 0)
- Secondary Outcome Measures
Name Time Method Proportion of patients presenting functional bowel disorder At baseline (day 0) Proportion of reasons of non-vaccination, globally and for each type of vaccination. At baseline (day 0) Proportion of vaccinated patients who present a good medication adherence to RA specific therapies At baseline (day 0) Proportion of factors influencing rheumatologists to propose vaccination. At baseline (day 0) Proportion of patients using electronic health tools who present a good medication adherence to RA specific therapies At baseline (day 0) Proportion of patients using electronic health tools At baseline (day 0) Proportion of patients with a special diet, globally and by type of diet At baseline (day 0) Proportion of patients vaccinated against influenza and pneumococcal bacteria At baseline (day 0) Proportion of patients with a special diet who present a good medication adherence to RA specific therapies At baseline (day 0) Number of patients with a good medication adherence, according to alcohol and/or tobacco consumption At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a good medication adherence, according to DAS28 score levels At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients for each personality trait category At baseline (day 0) Personality trait categories will be evaluated by the French version of Big Five Inventory questionnaire.
Number of patients using electronic health tools, according to each personality trait category At baseline (day 0) Personality trait categories will be evaluated by the French version of Big Five Inventory questionnaire
Number of patients with a good medication adherence, according to age At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a good medication adherence, according to gender At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a good medication adherence, according to involvement in a patients association At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a special diet, according to each personality trait category At baseline (day 0) Personality trait categories will be evaluated by the French version of Big Five Inventory questionnaire
Number of patients with a good medication adherence, according to educational level At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a good medication adherence, according to the use of alternative therapies (acupuncture and/or sophrology). At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a vaccination coverage, according to each personality trait category. At baseline (day 0) Personality trait categories will be evaluated by the French version of Big Five Inventory questionnaire.
Number of patients with a good medication adherence, according to each personality trait category At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires. Personality trait categories will be evaluated by the French version of Big Five Inventory questionnaire.
Number of patients with a good medication adherence, according to socio-professional category At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a good medication adherence, according to disease duration At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a good medication adherence, according to rheumatoid factor and/or ACPA positivity At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Number of patients with a good medication adherence, according to actual RA treatments At baseline (day 0) Medication adherence will be evaluated with medication adherence questionnaires
Trial Locations
- Locations (3)
CHU de Bordeaux - service de rhumatologie
🇫🇷Bordeaux, France
Service de Rhumatologie
🇫🇷Toulouse, France
Service de rhumatologie
🇫🇷Montpellier, France