Impact of Behavioral Factors on Treatment Adherence in a Sample of Rheumatoid Arthritis Patients

Brief Summary

Detailed Description

Rheumatoid arthritis (RA) care has been revolutionized in the last decade with the advent of biotherapies. The success of this therapeutic strategy is based on several factors, including the medication adherence. Whatever the method used, adherence evaluation is not sufficient, around 66% of the treated patients. Nevertheless, studies analysing the predictive factors of medication adherence in RA are rare. RA patients are also educated about the infectious risk related to RA and treatments, and the importance of vaccination. These recommendations are not always respected by the patients, without knowing the exact factors leading to this decision. Furthermore, a lot of patients take personal initiatives without the agreement and the help of their practitioner, like diets or special feeding behaviors. Lastly, plenty of patients affected bv chronic diseases claim and use electronic health tools without any real evidence of the efficacy of such device. The aim of this study is thus to evaluate RA treatment adherence considering demographic data, vaccination coverage, feeding behavior and the use of e-health tools.

Primary Outcomes

Secondary Outcomes

• Proportion of patients presenting functional bowel disorder(At baseline (day 0))
• Proportion of reasons of non-vaccination, globally and for each type of vaccination.(At baseline (day 0))
• Proportion of vaccinated patients who present a good medication adherence to RA specific therapies(At baseline (day 0))
• Proportion of factors influencing rheumatologists to propose vaccination.(At baseline (day 0))
• Proportion of patients using electronic health tools who present a good medication adherence to RA specific therapies(At baseline (day 0))
• Proportion of patients using electronic health tools(At baseline (day 0))
• Proportion of patients with a special diet, globally and by type of diet(At baseline (day 0))
• Proportion of patients vaccinated against influenza and pneumococcal bacteria(At baseline (day 0))
• Proportion of patients with a special diet who present a good medication adherence to RA specific therapies(At baseline (day 0))
• Number of patients with a good medication adherence, according to alcohol and/or tobacco consumption(At baseline (day 0))
• Number of patients with a good medication adherence, according to DAS28 score levels(At baseline (day 0))
• Number of patients for each personality trait category(At baseline (day 0))
• Number of patients using electronic health tools, according to each personality trait category(At baseline (day 0))
• Number of patients with a good medication adherence, according to age(At baseline (day 0))
• Number of patients with a good medication adherence, according to gender(At baseline (day 0))
• Number of patients with a good medication adherence, according to involvement in a patients association(At baseline (day 0))
• Number of patients with a special diet, according to each personality trait category(At baseline (day 0))
• Number of patients with a good medication adherence, according to educational level(At baseline (day 0))
• Number of patients with a good medication adherence, according to the use of alternative therapies (acupuncture and/or sophrology).(At baseline (day 0))
• Number of patients with a vaccination coverage, according to each personality trait category.(At baseline (day 0))
• Number of patients with a good medication adherence, according to each personality trait category(At baseline (day 0))
• Number of patients with a good medication adherence, according to socio-professional category(At baseline (day 0))
• Number of patients with a good medication adherence, according to disease duration(At baseline (day 0))
• Number of patients with a good medication adherence, according to rheumatoid factor and/or ACPA positivity(At baseline (day 0))
• Number of patients with a good medication adherence, according to actual RA treatments(At baseline (day 0))