Effect of rectal indomethacin and intravenous hydration in the prevention of pancreatitis after endoscopic retrograde cholangiopancreatography (single blind clinicaltrial)
Phase 3
- Conditions
- Calculus of bile duct without cholangitis or cholecystitis.Choledocholithiasis
- Registration Number
- IRCT2014082418915N1
- Lead Sponsor
- Mashad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 406
Inclusion Criteria
Age>18y; Patients are eligible if they are diagnosed with choledocolithiasis. Exclusion criteria: Patients with previous unsuccessful sphincterotomy; Decreased state of consciousness; Cardiovascular, renal diseases and under dialysis patients; Increased risk of bleeding; Evident acute pancreatitis, chronic pancreatitis or pancreatic cancer; Hyperamylasemia (= 150 IU/L); Allergy or hypersensitivity to indomethacin or water-soluble contrast solutions; Having ingested NSAIDs a week earlier are enrol
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of post endoscopic retrograde cholangiopancreatography pancreatitis. Timepoint: 2,12,24 hours post endoscopic retrograde cholangiopancreatography. Method of measurement: Clinical exam and serum amylase measurement.
- Secondary Outcome Measures
Name Time Method