Role of indomethacin suppository as a possible means to reduce complications related to Pancreatoduodenectomy.
Phase 2
- Conditions
- Health Condition 1: K860- Alcohol-induced chronic pancreatitisHealth Condition 2: K862- Cyst of pancreasHealth Condition 3: C241- Malignant neoplasm of ampulla of VaterHealth Condition 4: C240- Malignant neoplasm of extrahepaticbile ductHealth Condition 5: C250- Malignant neoplasm of head of pancreasHealth Condition 6: K831- Obstruction of bile ductHealth Condition 7: K861- Other chronic pancreatitisHealth Condition 8: K838- Other specified diseases of biliary tract
- Registration Number
- CTRI/2020/09/028027
- Lead Sponsor
- Institute of Liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All consenting adults planned to undergo pancreatoduodenectomy
Exclusion Criteria
1. Patients refusing to consent
2. History of asthma
3. History of allergic reactions to NSAIDs
4. History of renal dysfunction or CKD
5. E/o Internal hemorrhoids on examination
6. Patients on Anti-platelet drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of Post-operative PancreatitisTimepoint: Within 30 days of surgery
- Secondary Outcome Measures
Name Time Method Delayed Gastric emptying rateTimepoint: within 30 days of surgery;Duration of ICU stayTimepoint: within 30 days of surgery;Intra-abdominal collections/abscess ratesTimepoint: within 30 days of surgery;Length of Hospital StayTimepoint: within 30 days of surgery;Post-operative pancreatic fistula rateTimepoint: within 30 days of surgery;Post-pancreaticoduodenectomy hemorrhage rateTimepoint: within 30 days of surgery;Risk factors for post-operative pancreatitisTimepoint: within 30 days of surgery