A study to compare the effects and safety of of Injection Levetiracetam and Injection Magnesium Sulphate in the prevention of fits in pregnant women with high blood pressure
Phase 1
- Conditions
- Health Condition 1: O141- Severe pre-eclampsia
- Registration Number
- CTRI/2024/04/064992
- Lead Sponsor
- BLDE(DU) Shri BM Patil medical College, Hospital and Resarch Center, Vijayapura
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Pregnant women with gestational age of more than or equal to 28 weeks presenting with features of severe pre-eclampsia and/ or imminent eclampsia, needing immediate delivery as per treating clinician’s decision
2. No contraindication to either of the study drugs
3.Patients giving written informed consent for investigations and the proposed intervention
Exclusion Criteria
1.Patients diagnosed with other causes of convulsions in pregnancy like cerebral malaria and epilepsy
2.Pregnant women with chronic hypertension without super-imposed pre-eclampsia
3.Pregnant females with fetal anomalies detected on USG
4.Pregnant women who already have deranged renal parameters
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effeciacy and safety of Levetiracetam in prevention of seizures in PreeeclampsiaTimepoint: WIthin 30 min of administeting the drug. At 24 hours of administering the drug. At delivery of the baby
- Secondary Outcome Measures
Name Time Method To observe the adverse effects of Levetiracetam and Magnesium sulphateTimepoint: For 5 days