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Clinical Trials/NCT01976052
NCT01976052CompletedNot Applicable

Evaluation of Potential Biomarkers for Obstructive Sleep Apnea and the Effect of Positive Pressure Treatment

Karolinska University Hospital1 site in 1 country75 target enrollmentStarted: October 1, 2013Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
75
Locations
1
Primary Endpoint
Biomarker
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Potential biomarkers for obstructive sleep apnea (OSA), and full genomic screening will be evaluated and correlated to the degree of OSA and to effect of CPAP-treatment measured by polygraphy.

Detailed Description

This project includes two parts:

  • Genomic screening
  • Biomarkers

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 75 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • •If they no not fulfil the inclusion criteria

Outcomes

Primary Outcomes

Biomarker

Time Frame: Comparison between 0, 3 and 12 month

Biomarkers related to inflammation, hypoxia, oxidative stress, redox and the central nervous system will be measured

Secondary Outcomes

  • Genomics(Comparison between 0, 3, 12 month)
  • Apnea hypopnea index(Comparision between 0, 3 and 12 month)
  • Exhaled nitric oxide(Comparision at 0, 3 and 12 month)

Investigators

Sponsor
Karolinska University Hospital
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Malin Jonsson Fagerlund

MD, PhD

Karolinska University Hospital

Study Sites (1)

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