The effect of intracameral anesthesia on macular thickness and ganglion cell-inner plexiform layer thickness after uneventful phacoemulsification surgery
- Conditions
- Senile cataractEye Diseases
- Registration Number
- ISRCTN94155463
- Lead Sponsor
- Balikesir University (Turkey)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 100
Patients requiring phacoemulsification surgery for the treatment of senile cataract were included. Inclusion criteria were the presence of senile cataract between 45 and 85 years of age and a clear fundus examination before the surgery.
Exclusion criteria were
1. Pre-existing macular diseases such as macular edema, epiretinal membrane, macular hole and age-related macular degeneration
2. Ocular diseases such as diabetic retinopathy, glaucoma and previous uveitis
3. Pre-existing refractive error: ±3.00 dioptries
4. History of previous intraocular surgery (except cataract surgery in the fellow eye within the previous 6 months) or laser treatment
5. Diabetes, hypertension or other systemic disease that could affect the eye and topical and/or systemic medications with known interference on macular thickness such as steroids and diuretics.
6. Patients with operative complications and eyes with media opacities which could reduce the signal strength and lead to a segmentation error in preoperative measurements were also excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Macular thickness analyses with spectral domain optical coherence tomography measured at baseline and at 1 day, 2 days, 1 week, 1 month and 3 months after surgery.
- Secondary Outcome Measures
Name Time Method Ganglion cell-inner plexiform layer and peripapiller retinal nerve fiber layer thickness analyses as well as visual acuity changes measured at baseline and at 1 day, 2 days, 1 week, 1 month and 3 months after surgery.