NL-OMON22720
Recruiting
N/A
A randomized clinical trial examining the outcome of immediate versus early (24 to 48 hours) percutaneous coronary intervention in patients with an acute coronary syndrome without persistent ST-segment elevation.
Not provided0 sites600 target enrollmentTBD
ConditionsSTE-ACS
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- STE-ACS
- Sponsor
- Not provided
- Enrollment
- 600
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
/A
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age \> 21 years;
- •2\. Typical chest pain for angina pectoris lasting at least 10 minutes, within last 6 hours;
- •3\. No contra\-indication to PCI;
- •And at least one of the following criteria:
- •1\. 1 mm of horizontal or downsloping ST depression;
- •2\. Dynamic ST\- or T\- wave changes \> 1 mm in two contiguous leads;
- •3\. Elevated troponin or CK\-Mb;
- •4\. Known coronary artery disease;
- •5\. Two of following risk factors: DM, known hypertension, current smoking, family hx, hypercholesterolaemia, peripheral artery disease, age over 60 years.
Exclusion Criteria
- •1\. Chest pain suspected not to be caused by CAD;
- •2\. Acute myocardial infarction requiring reperfusion therapy;
- •3\. Thrombolytic therapy \<24 hours / indication for trombolytic therapy;
- •4\. Recent PCI (\<14 days);
- •5\. Thrombopenia (\<100\*1012/mm3\);
- •6\. Severe bleeding \< 6 weeks;
- •7\. Major surgery \< 6 weeks;
- •8\. Cerebral haemorrhage in medical history;
- •9\. High blood pressure left untreated;(diastolic \> 100 mmHg, systolic \> 180 mmHg);
- •10\. Life expectancy \< 1 year due to co morbidity;
Outcomes
Primary Outcomes
Not specified
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