NL-OMON22720招募中不适用
A randomized clinical trial examining the outcome of immediate versus early (24 to 48 hours) percutaneous coronary intervention in patients with an acute coronary syndrome without persistent ST-segment elevation.
未提供0 个研究点目标入组 600 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 600
研究概览
简要总结
/A
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Age > 21 years;
- •2. Typical chest pain for angina pectoris lasting at least 10 minutes, within last 6 hours;
- •3. No contra-indication to PCI;
- •And at least one of the following criteria:
- •1. 1 mm of horizontal or downsloping ST depression;
- •2. Dynamic ST- or T- wave changes > 1 mm in two contiguous leads;
- •3. Elevated troponin or CK-Mb;
- •4. Known coronary artery disease;
- •5. Two of following risk factors: DM, known hypertension, current smoking, family hx, hypercholesterolaemia, peripheral artery disease, age over 60 years.
排除标准
- •1. Chest pain suspected not to be caused by CAD;
- •2. Acute myocardial infarction requiring reperfusion therapy;
- •3. Thrombolytic therapy <24 hours / indication for trombolytic therapy;
- •4. Recent PCI (<14 days);
- •5. Thrombopenia (<100*1012/mm3);
- •6. Severe bleeding < 6 weeks;
- •7. Major surgery < 6 weeks;
- •8. Cerebral haemorrhage in medical history;
- •9. High blood pressure left untreated;(diastolic > 100 mmHg, systolic > 180 mmHg);
- •10. Life expectancy < 1 year due to co morbidity;
- •11. Known intracranial malformation or -neoplasm;
- •12. Participation in other study possibly interfering with the endpoints;
- •13. Inability to follow up;
- •14. Culprit lesion is a restenotic lesion.
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