Vitamin D supplementation in type 2 Diabetes Mellitus.
Completed
- Conditions
- Type 2 diabetes mellitusInsulin resistanceVitamin D deficiency
- Registration Number
- NL-OMON26335
- Lead Sponsor
- S.SimsekMedisch Centrum Alkmaar
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 300
Inclusion Criteria
1. Written informed consent;
2. Patients with T2DM treated with lifestyle advises whether or not in combination with metformin;
Exclusion Criteria
1. Impaired renal function: creatinine * 150 *mol/l or an estimated creatinin clearance < 50 ml/min, to the discretion of the investigator;
2. Cardiac problems:
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method HbA 1c values.
- Secondary Outcome Measures
Name Time Method 1. The effect of vitamin D supplementation on serum 25OHD, insulin sensitivity, bloodpressure, thyroid function, lipid profile and BMI in patients with type 2 diabets melltius;<br /><br>2. Adverse effects.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways does vitamin D modulate in improving insulin resistance in T2DM patients in NL-OMON26335?
How does vitamin D supplementation compare to metformin in glycemic control for T2DM patients with deficiency in NL-OMON26335?
Which biomarkers correlate with improved glycemic control in T2DM patients receiving vitamin D supplementation in NL-OMON26335?
What are the safety profiles and adverse event management strategies for high-dose vitamin D in T2DM patients in NL-OMON26335?
Are there synergistic effects of combining vitamin D with GLP-1 agonists in T2DM and insulin resistance management in NL-OMON26335?