Lifestyle Physical Activity for People With COPD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COPD
- Sponsor
- University of Michigan
- Enrollment
- 54
- Locations
- 1
- Primary Endpoint
- Change in physical activity measured by accelerometry
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this preliminary study is to examine the effects of a program that includes two-months of structured lab-based training. The proposed study will examine the effects of a lifestyle physical activity intervention designed to increase PA in people with moderate and severe COPD. The intervention includes a combination of (a) structured laboratory-based exercises with a behavioral intervention, (b) structured home-based exercises and (c) lifestyle physical activities performed at home. The subjects will be followed for a total of 18 weeks.
Detailed Description
People with chronic obstructive pulmonary disease (COPD) experience a gradual decline in physical activity (PA). Exercise training in a structured pulmonary rehabilitation program can generate substantial gains in functional capacity, but increases in functional capacity do not necessarily lead to improvements in daily PA. The proposed study will examine the effects of a lifestyle physical activity intervention designed to increase PA in people with moderate and severe COPD. The intervention includes a combination of (a) structured laboratory-based exercises with a self-efficacy enhancing intervention, (b) structured home-based exercises and (c) lifestyle physical activities performed at home. The intervention gradually transitions subjects from the structured laboratory-based exercises that focus on walking and circuit training to fully integrated lifestyle physical activities that integrate structured home-based exercises and lifestyle physical activities into daily life. The purpose of this preliminary study is to examine the effects of a program that includes two-months of structured lab-based training and subjects will be followed for a total of 18 weeks.
Investigators
Janet L. Larson
Professor
University of Michigan
Eligibility Criteria
Inclusion Criteria
- •55 years or older
- •Moderate to severe COPD (FEV1 \< 80% and \> 30% predicted; FEV1/FVC \<70%) as the primary health problem
- •Sedentary (less than 30 minutes of moderate activity 3 days/week)
Exclusion Criteria
- •No acute exacerbations or major illnesses requiring hospitalization in the last 8 weeks.
- •No history of other major lung diseases as primary pulmonary problem, history of a recent heart attack or recent onset of chest pains with activity or increasing episodes of chest pain (unstable angina).
- •No other health problems or mobility problems that limit physical activity.
- •No child bearing potential
Outcomes
Primary Outcomes
Change in physical activity measured by accelerometry
Time Frame: During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18
Subjects wear two activity monitors for seven consecutive days (Actipal and Actigraph). The study will compare the subject's activity level at the three time points listed.
Secondary Outcomes
- Change in dyspnea and fatigue (Pulmonary Functional Status and Dyspnea Questionnaire-Modified)(During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18)
- Change in physical activity measured by CHAMPS questionnaire(During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18)
- Change in 6 minute walk test(During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18)
- Change in lower extremity function (Short Physical Performance Battery)(During initial visit (week 1), at 6 or 10 weeks (depending on group placement), and at week 18)