Skip to main content
Clinical Trials/NCT01381133
NCT01381133
Completed
Phase 3

Adolescent Outpatient and Continuing Care Study

Chestnut Health Systems1 site in 1 country320 target enrollmentSeptember 2002

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Substance Abuse
Sponsor
Chestnut Health Systems
Enrollment
320
Locations
1
Primary Endpoint
Change in Percentage of days abstinent from any alcohol and drugs
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The purpose of this study was to evaluate the effectiveness and cost-effectiveness of two types of outpatient treatment with and without Assertive Continuing Care (ACC) for 320 adolescents with substance use disorders. Study participants were randomly assigned to one of four conditions: (a) Chestnut's Bloomington Outpatient Treatment (CBOP) without ACC; (b) CBOP with ACC; (c) Motivational Enhancement Therapy/Cognitive Behavior Therapy-7 session model (MET/CBT7) without ACC; and (d) MET/CBT7 with ACC. Based on prior quasi and experimental studies, the investigators hypothesized that MET/CBT would be more effective and cost-effective than CBOP in terms of increasing days abstinent and decreasing substance abuse problems. Additionally, the investigators hypothesized that the groups receiving ACC would have significantly better outcomes than the groups without ACC. Lastly, the investigators hypothesized that adding ACC to MET/CBT would be the most cost-effective option in terms of days abstinent.

Detailed Description

This study evaluated the effectiveness and cost-effectiveness of two types of outpatient treatment with and without Assertive Continuing Care (ACC) for 320 adolescents with substance use disorders. Study participants were randomly assigned to one of four conditions: (a) Chestnut's Bloomington Outpatient Treatment (CBOP) without ACC; (b) CBOP with ACC; (c) Motivational Enhancement Therapy/Cognitive Behavior Therapy-7 session model (MET/CBT7) without ACC; and (d) MET/CBT7 with ACC. All study conditions attained high rates of participant engagement and retention. Follow-up interviews were completed with over 90% of the adolescents at three, six, nine, and 12 months after treatment admission. There was a significant time by condition effect over 12 months, with CBOP having a slight advantage for average percentage of days abstinent. Unlike previous findings that ACC provided incremental effectiveness following residential treatment, there were no statistically significant findings with regard to the incremental effectiveness of ACC following outpatient treatment. Analysis of the costs of each intervention combined with its outcomes revealed that the most cost-effective condition was MET/CBT7 without ACC.

Registry
clinicaltrials.gov
Start Date
September 2002
End Date
December 2008
Last Updated
12 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 12-18 years old
  • met ASAM's (2001) Patient Placement Criteria for Level I outpatient treatment based on a substance abuse or dependence diagnosis and six dimensional admission criteria (i.e., severity of intoxication/withdrawal, physical health, emotional/behavioral health, treatment readiness, relapse potential, and recovery environment)
  • attended an admission appointment

Exclusion Criteria

  • "stepped-down" from residential treatment and were therefore more severe than adolescents who entered outpatient treatment from the community
  • were recommended only for individual counseling, as both outpatient treatment conditions had group components
  • were a ward of the state
  • did not have a parent/guardian present during admission to outpatient treatment
  • appeared to have insufficient mental capacity to provide informed consent
  • did not speak English with sufficient ability to understand study procedures and instruments

Outcomes

Primary Outcomes

Change in Percentage of days abstinent from any alcohol and drugs

Time Frame: Baseline and 3, 6, 9, and 12 months post-baseline

Change in Days abstinent from alcohol alone

Time Frame: Baseline and 3, 6, 9, and 12 months post-baseline

Change in Substance use problems

Time Frame: Baseline and 3, 6, 9, and 12 months post-baseline

Measured using the Substance Problem Scale of the Global Appraisal of Individual Needs

Change in Recovery status

Time Frame: 12 months post-baseline

Being in recovery at the end of the study was defined as living in the community (vs. being incarcerated, or residing in inpatient treatment or other controlled environment) and reporting no past month substance use, abuse, or dependence problems at the 12 month interview. Urine samples were collected as described above in Section 2.4.2, and when an adolescent reported being in recovery but the urine test result suggested a false-negative self-report, data were re-coded to show the adolescent as not being in recovery.

Study Sites (1)

Loading locations...

Similar Trials