Dutch- Belgian pediatric acute myeloid leukemia (AML) protocol.
- Conditions
- ewly diagnosed acute myeloid leukaemia in children and adolescents.
- Registration Number
- NL-OMON28546
- Lead Sponsor
- Stichting Kinderoncologie Nederland (SKION)
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 110
Inclusion Criteria
1. Primary diagnosed AML as defined by the diagnostic criteria;
2. Age lower than 19 years at time of study entry;
Exclusion Criteria
1. Previous chemo- or radiotherapy;
2. AML secondary to previous bone marrow failure syndrome;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To conduct an international pediatric study for AML based on the NOPHO-AML 2004 protocol with optimal outcome and less toxicity;<br /><br>2. To reduce cumulative anthracycline dosage<br>to reduce the number of intensive courses to 5.<br>
- Secondary Outcome Measures
Name Time Method To monitor cardiotoxicity by echocardiography.