Drug-induced Kidney Injury Model
Recruiting
- Conditions
- Acute Kidney Injury
- Registration Number
- NCT06939387
- Lead Sponsor
- Zhejiang Provincial People's Hospital
- Brief Summary
To establish the prediction model of renal dysfunction in patients with drug-induced renal injury and study the prognosis of different drug treatments
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1500
Inclusion Criteria
- Drug-induce acute kidney injury
Exclusion Criteria
- 1.Dialysis patients; 2.No baseline creatinine; 3.Obstructive AKI; 4.Clinical data were incomplete.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Model performance metrics assessed by AUC-ROC, accuracy and F1-score using 10-fold cross-validation through study completion, an average of 6 months The prognosis of renal function was evaluated by measuring creatinine and proteinuria by laboratory tests. Predict outcomes using machine learning methods. And the prediction effect of the prediction model was evaluated by AUC-ROC, F1, accuracy and other indicators.
- Secondary Outcome Measures
Name Time Method The rate at which creatinine falls 7 days, 1 month, 3 months after treatment
Trial Locations
- Locations (1)
Zhejiang Provincial People's Hospital
🇨🇳Hangzhou, Zhejiang, China