Assessing in young Australian adults whether exposure to simulated solar ultraviolet radiation affects immune response to primary vaccination.
Not Applicable
Completed
- Conditions
- Impact of solar ultraviolet radiation on human primary immune response to immunisation with a T-dependent antigen (Keyhole Limpet Haemocyanin)Inflammatory and Immune System - Normal development and function of the immune system
- Registration Number
- ACTRN12609000380291
- Lead Sponsor
- Dr Ashwin Swaminathan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
* Age 18 - 40 years
* Fitzpatrick Type II-III skin (fair skin which sunburns without difficulty)
* Willing and able to sign informed consent
Exclusion Criteria
* Allergy to shellfish
* Pregnancy or breastfeeding
* Previous KLH vaccination
* Immunosuppressive medications
* Immunosuppressive medical condition
* Recent infection (within 2 weeks of vaccination)
* Recent immunisation with any other vaccine in past 4 weeks
* Photosensitive skin or taking photosensitsing medication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method