Clinical trial to study effect of levobupivacaine versus adding ketamine to levobupivacaine to relieve post operative pain in one sided total knee replacement patients by using ultrasound guided adductor canal block
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/05/052456
- Lead Sponsor
- Department of Anesthesiology and critical care, AIIMS Bathinda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA 1 & 2
2. U/L TKR patients under spinal anesthesia
3. Patient age between 18 to 75 years
Exclusion Criteria
1. Patient with known allergic reaction history to
lignocaine, levobupivacaine & ketamine
2. Body mass index (BMI) >35kg/m2
3. Pre-existing peripheral neuropathy or
neurological deficit in lower extremities
4. Coagulopathy
5. Infection at site of block
6. Refusal for consent
7. Psychiatric disorder
8. Prior knee surgery on same limb or lower
limb deformity of the same limb
9. Pregnancy and lactating mothers
10. Use of any regional block other than ACB as
postoperative analgesia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare duration of post operative analgesia using levobupivacaine and levobupivacaine plus ketamine as adjuvant in adductor canal block in unilateral total knee replacement patientsTimepoint: Note time when numeric rating scale is more than or equal to 4 <br/ ><br>time point: 24 hours
- Secondary Outcome Measures
Name Time Method To assess amount of rescue analgesia (Tramadol as rescue analgesia) required after using levobupivacaine and levobupivacaine plus ketamine as adjuvant in adductor canal block in unilateral total knee replacement patientsTimepoint: Time of first dose & total tramadol consumption noted in 24 hours after surgery