Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients

Mongi Slim Hospital1 site in 1 country36 target enrollmentApril 1, 2017

Overview

Brief Summary

This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation.

Detailed Description

This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation. The investigators compared the median values of DE and DTF in the group of successfully extubated patients and the group of patients who needed reintubation. Our study compared the utility of DTF and DE to predict extubation success.

Registry

clinicaltrials.gov

Start Date

April 1, 2017

End Date

December 31, 2017

Last Updated

8 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Mongi Slim Hospital

Responsible Party

Principal Investigator

Mhamed Sami Mebazaa

Professor head of the anesthesia and intensive care department

Mongi Slim Hospital

Eligibility Criteria

Inclusion Criteria

•patients who were mechanically ventilated for more than 48h and meeting all criteria for extubation
•patients without history of neuromuscular disease, or severe chronic respiratory failure