Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- extubation success
研究概览
简要总结
This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation.
详细描述
This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation. The investigators compared the median values of DE and DTF in the group of successfully extubated patients and the group of patients who needed reintubation.
Our study compared the utility of DTF and DE to predict extubation success.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who were mechanically ventilated for more than 48h and meeting all criteria for extubation
- •patients without history of neuromuscular disease, or severe chronic respiratory failure
排除标准
- •patients who needed reintubation for upper airway obstruction or neurological or hemodynamic instability
结局指标
主要结局
extubation success
时间窗: 48 hours after extubation
comparaison between DE and DTF values in successfully extubated patients
次要结局
未报告次要终点
研究者
Mhamed Sami Mebazaa
Professor head of the anesthesia and intensive care department
Mongi Slim Hospital