The Impact of Preoperative Supplementation of Zinc

Not Applicable

Completed

• Conditions: Surgery; Nutrition Disorders
• Interventions: Dietary Supplement: Zinc

• Registration Number: NCT05785013
• Lead Sponsor: Cairo University

Brief Summary

1. Pre operative anthropometric assessment including : weight in kg, height/length and BMI

2. Pre operative Zinc supplementation (dose according to the age) for 7 days preoperatively for cases

3. Postoperative data collection

Detailed Description

Postoperative data collection :

* Length of hospital stay

* Complication and sorting of them

* Lab withdrawal of inflammatory markers on 2-3 day postoperatively

Study Timeline

• Study First Submitted: 2023-03-02
• Study First Submitted QC: 2023-03-14
• Study First Posted: 2023-03-27
• Study Start: 2023-04-01
• Primary Completion: 2023-06-30
• Study Completion: 2023-07-02
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-08
• Last Update Posted: 2024-02-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

1. All children patients with Hirschsprung disease admitted for surgical intervention with different ( age , sex )
2. Type of surgery : transanal pull through
3. Whose parents or caregivers approve for the participation in the study

Exclusion Criteria

1. Patients with emergency situations
2. Whose parents or caregivers will not apply for the participation in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Interventional	Zinc	25 children diagnosed with Hirschsprung disease and planned for elective surgery will be supplemented with Zinc 7 days before the operation . Outcomes will be evaluated thorugh measuring the hospital length stay. Other parameters including inflammatory markers as CRP , CRP /albumin ratio and development of postoperative complications will be assesed and compared between cases and controls

Primary Outcome Measures

Name	Time	Method
The effect of preoerative Zinc supplementation on the hospital length stay in children operated for Hirschsprung's disease	zinc supplemenation for one week	Children oprated for elective surgery for Hirschsprung's disease will be supplemented with zinc seven days before surgery and postoperative data as the duration of hospital length stay in hours will be meausred in both the cases and control groups and comapred.

Trial Locations

Locations (1)

Hoda Atef Abdelsattar Ibrahim; 🇪🇬 Cairo, Egypt