Investigating the effect of probiotics and prebiotics on signs and symptoms of dry eye disease in adults

SW School of Optometry and Science Vision0 个研究点目标入组 41 人开始时间: 2024年4月10日最近更新: 2024年4月15日

试验速览

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•-be able to read and comprehend English and give informed consent as demonstrated by signing a record of informed consent
•-No previous probiotic or fermented product intake in the last three months
•-Currently have been diagnosed with dry eye disease
•-Be at least 18 years old
•-Be willing to comply with the consuming probiotic product and clinical trial visit schedule
•-Be willing to discontinue all ophthalmic preparations including artificial tears during the study and 72 hours before screening

•- Currently taking probiotics or other fermented products. Participants will be advised not to change their diet for the duration of the study.
•-Any systemic or topical medications that will affect ocular physiology or tear film layer e.g. anti-acne medications such as Roaccutane and corticosteroids or immunosuppressant medications such as Hydrocortisone, Prednisolone.
•-Any systemic disease that may affect ocular health e.g. diabetes, Graves’ disease, and auto-immune diseases such as ankylosing spondylitis, multiple sclerosis, Sjögren’s syndrome, Crohn’s disease, elevated CRP, IBS, Inflammatory bowel disease and systemic lupus erythematosus.
•-Eye surgery within 12 weeks immediately prior to enrolment for this trial
•-Previous corneal refractive surgery
•-Active corneal infection or any active ocular disease such as iritis, corneal edema or corneal dystrophies, including anterior membrane dystrophy
•-Any current ocular injury
•-Taking oral or topical antibiotics
•-Be currently enrolled in another clinical trial or have participated in a clinical trial within the previous 2 weeks.
•-pregnant or lactating

发起方

SW School of Optometry and Science Vision