The effects of using a probiotic compared to a prebiotic on the symptoms in people with Irritable Bowel Syndrome

Not Applicable

Recruiting

• Conditions: Constipation; K58.9

• Registration Number: RBR-6srwt2n
• Lead Sponsor: Hospital de Clínicas da Universidade Federal do Paraná

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-03-07
• Last Update Posted: 2 April 2024
• Study Completion: 2025-12-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

age older than 18 years; eutrophic or overweight with body mass index between 18.5 and 29.9 kg/m²; with I rritable Bowel Syndrome C symptoms according to Rome IV criteria; with complete primary education

Exclusion Criteria

other gastrointestinal diseases; kidney disease; liver diseases; gastrointestinal tract surgery; allergies to gluten and lactose; have used antibiotics or prebiotics or probiotics or symbiotics in the last 4 weeks; scleroderma

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the gastrointestinal tolerance and the ability of the prebiotic to alleviate symptoms of IBS-C (Irritable Bowel Syndrome with constipation predominance), in comparison to the probiotic Lactobacillus rhamnosus GG - The assessment of gastrointestinal symptoms will be conducted using previously developed questionnaires that include the Gastrointestinal Symptom Rating Scale (GSRS), the Irritable Bowel Syndrome Symptom Severity Scale (IBS-SSS), and the Bristol Stool Scale. These questionnaires will be administered before and after each supplementation period (weeks 0, 4, 8, 12, and 24).