NCT00284726已完成3 期
A Prospective, Controlled, Randomized Study on the Effect of Cold Storage Solutions on Complement Activation and Other Mediators of Ischemic Injury in Lung Transplantation
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
研究概览
简要总结
The purpose of this study is to compare 2 different cold storage solutions, used to preserve donor lungs for lung transplantation, and their effect on cytokine activation related to ischemic reperfusion injury. Primary endpoint is 30 day survival.
详细描述
The length of ischemic time in harvesting lung allografts is associated with graft survival. It is further thought that ischemic changes in early post-transplantation bronchoscopic biopsies has a direct correlation with later development of chronic rejection.
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any patient undergoing a lung trasnplant at Johns Hopkins Hospital -
排除标准
- 未提供
研究者
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