Injectable autologous platelet concentrate as an adjunct to periodontal flap surgery in the management of periodontitis
Phase 3
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2022/11/047091
- Lead Sponsor
- Dr Anu John
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Adults above18 years diagnosed with periodontitis (according to AAP 2017 classification) after step 1 and step 2 therapy (non-surgical phase) with the presence of atleast one site with 2 or 3 walled interproximal infrabony defects in either of the jaws
2.Systemically healthy subjects
3.Full mouth bleeding score<= 30 % and Full mouth plaque score <=20%
Exclusion Criteria
1.Current tobacco users
2.Subjects taking medications affecting the periodontium (Bisphosphonates, Calcium channel blockers, cyclosporine, steroids, phenytoin )
3.Pregnancy or lactation
4.Antibiotic medication in the last 3 months
5.Infrabony defects that are indicated for resective therapy.
6.Grade II /II furcation involvement
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Clinical attachment gainTimepoint: 6 months
- Secondary Outcome Measures
Name Time Method 1.Probing pocket depth reduction <br/ ><br>2.Gingival recession <br/ ><br>3.Radiographic bone fill <br/ ><br>4.Composite outcome measureTimepoint: 6 months