Spirometry screening for post-tuberculosis lung disease among adolescents and adults in Mozambique

Not Applicable

• Conditions: Pulmonary lung function screening (spirometry) in persons completing 6 months of treatment for active TB; Infections and Infestations

• Registration Number: ISRCTN92021748
• Lead Sponsor: Tulane University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2024-09-16
• Last Update Posted: 30 September 2024
• Study Completion: 2025-06-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 115

Inclusion Criteria

Primary outcome: 1. Aged =15 years of age2. Enrolled in the National TB Control Program (NTCP) at Carmelo Hospital (CHC) with a GeneXpert-positive sputum3. Completed six months of TB treatment and considered TB-cured4. Ability to understand and comply with study proceduresSemi-structured key-informant interviews:1. Participants at the central level of the NTCP in Maputo (Mozambique’s capital city)2. Administrators of CHC and at each of the three selected peripheral health facilities3. Clinicians (physician, medical technician, and nurse) responsible for implementing the spirometry screening program at CHC, as well as all clinicians responsible for treating TB at each of the three selected peripheral health facilities

Exclusion Criteria

1. Less than 15 years of age2. Active respiratory symptoms at the time of screening that are indicative of a new acute respiratory illness

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of post-tuberculosis lung disease amongst persons completing 6 months of treatment for active TB measured using spirometry and symptom screening at baseline (completion of 6 months of TB treatment) and at 6 months after completion of TB treatment.