Aortic Dissection With 4-dimensional Phase-contrast Magnetic Resonance Imaging

Recruiting

• Conditions: MRI

• Registration Number: NCT04481542
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

We prospectively collected information on consecutive patients who had been evaluated using 4D PC-MRI for aortic pathology in a tertiary hospital between April 2018 and Feb 2020. Patients were eligible for inclusion in the study if they had a clinical indication for CTA of aortic dissections.

Detailed Description

The exclusion criteria were non-MRI-compatible ferromagnetic devices and pregnancy. In addition, patients with poor compliance and with unstable status that prevented them from lying down for the MRI protocol were excluded. Initially, 26 patients evaluated. One patient was excluded due to fever at the scheduled time, and another was unable to lie down due to complicated spine disease. All patients underwent CTA scan on a 64-slice multidetector scanner (Somatom Sensation 64; Siemens Healthcare, Erlangen, Germany) with the intravenous administration of contrast media, followed by 4D PC-MRI to assess aortic pathology

Study Timeline

• Study Start: 2018-03-01
• Primary Completion: 2020-02-12
• Study First Submitted: 2020-02-23
• Status Verified: 2020-03
• Study First Submitted QC: 2020-07-21
• Last Update Submitted: 2020-07-21
• Study First Posted: 2020-07-22
• Last Update Posted: 2020-07-22
• Study Completion: 2025-12-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
stroke volume	5 years	anatomic/hemodynamic parameter

Secondary Outcome Measures

Name	Time	Method
adverse event	5 years	diagnostic function

Trial Locations

Locations (1)

Yao-Kuang Huang; 🇨🇳 Chiayi City, Chiayi County, Taiwan