跳至主要内容
临床试验/NCT03666676
NCT03666676
已完成
不适用

Auditory Processing of Complex Sounds - Sensitivity to Chirps

University of Rochester1 个研究点 分布在 1 个国家目标入组 67 人2020年6月9日

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Hearing Loss, Sensorineural
发起方
University of Rochester
入组人数
67
试验地点
1
主要终点
F1 Discrimination Threshold
状态
已完成
最后更新
11个月前

概览

简要总结

The purpose of this study is to better understand the sensitivity of listeners to the fast changes in frequency or amplitude of sounds that occur in speech. The investigators are studying ways to manipulate these aspects of sounds in an effort to make speech sounds more clear.

详细描述

The investigators will test listeners with normal hearing or with mild or moderate hearing loss. Tests will first focus on sensitivity to changes in fast changes in amplitude (loudness) or frequency (pitch) in sounds. Then the investigators will test the intelligibility of synthetic vowels and syllables in which these "chirps" are manipulated. Finally, the investigators will test intelligibility of words in noise while manipulating sounds in an effort to improve clarity.

注册库
clinicaltrials.gov
开始日期
2020年6月9日
结束日期
2024年8月1日
最后更新
11个月前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Principal Investigator
主要研究者

Laurel Carney

Professor

University of Rochester

入排标准

入选标准

  • Normal hearing, mild or moderate symmetric sensorineural hearing loss.

排除标准

  • Asymmetric hearing thresholds (more than 15 decibels (dB) threshold difference between the two ears at any frequency up to 4 kHz).
  • Severe hearing loss (greater than 60 dB hearing thresholds at any frequency up to 4 kHz).

结局指标

主要结局

F1 Discrimination Threshold

时间窗: 6 months

Discrimination threshold for changes in F1, the low-frequency formant (spectral peak) in the synthetic vowel sounds.

F2 Discrimination Threshold

时间窗: 6 month

Discrimination thresholds in % frequency for F2, the higher-frequency peak in synthetic vowel stimuli.

Pure-tone Average Thresholds

时间窗: 6 months

Hearing thresholds, average across test frequencies from 250 to 4000 Hz and averaged across the two ears.

研究点 (1)

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