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临床试验/NCT05713383
NCT05713383
撤回
不适用

The Role of Perturbed Auditory Information for Self-motion in Gait

University of Nebraska1 个研究点 分布在 1 个国家目标入组 30 人2026年3月1日
适应症Gait
干预措施Auditory Feedback

概览

阶段
不适用
干预措施
Walking
疾病 / 适应症
Gait
发起方
University of Nebraska
入组人数
30
试验地点
1
主要终点
Gait instability measured with the maximum Lyapunov exponent (MLE)
状态
撤回
最后更新
3个月前

概览

简要总结

As people walk and interact with objects such as when opening a door, their movements make sounds. It is possible that these sounds are also used as feedback to stabilize and adapt movement. There is some evidence for such a connection between the auditory and motor systems in activities of daily living, yet the empirical work is insufficient because the role of the auditory system in movement is a relatively neglected topic. The objective of this study is to address this gap. The study will also evaluate the potential for improvements in movement stability and variability by restricting or augmenting the auditory feedback from the participants' footstep sounds.

详细描述

As people walk and interact with objects such as when opening a door, their movements make sounds. It is possible that these sounds are also used as feedback to stabilize and adapt movement. There is some evidence for such a connection between the auditory and motor systems in activities of daily living, yet the empirical work is insufficient because the role of the auditory system in movement is a relatively neglected topic. The objective of this study is to address this gap. The study will also evaluate the potential for improvements in movement stability and variability by restricting or augmenting the auditory feedback from the participants' footstep sounds. Eligibility is based on inclusion and exclusion criteria determined via a self-report questionnaire. The inclusion criteria are age and overall health status (young healthy adults, 19-35) and self-reported ability to walk comfortably for half an hour. Exclusion criteria include known hearing impairment, history of back or lower extremity injury, surgery that affects mobility, neurological disease or impairment that limits the ability to walk (Cerebral palsy). The study will randomly split the participants in a control and experimental group. Participants will perform trials in one condition only, quiet walking or control. Participants will visit the lab five times in the span of two weeks. The first and last sessions will serve for pre-post comparisons.

注册库
clinicaltrials.gov
开始日期
2026年3月1日
结束日期
2026年8月1日
最后更新
3个月前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Sponsor

入排标准

入选标准

  • self-reported tolerance to 30 minute exercise
  • self-reported ability to walk comfortably for half an hour

排除标准

  • known hearing or visual impairment
  • currently being pregnant
  • history of back or lower extremity injury, surgery that affects mobility, and neurological disease or impairment that limit the ability to walk

研究组 & 干预措施

Walking

Walking normally without restriction

Walking Quietly

Participants instructed to make little noise while walking.

干预措施: Auditory Feedback

结局指标

主要结局

Gait instability measured with the maximum Lyapunov exponent (MLE)

时间窗: The time frame to measure changes in the outcome variable is two weeks, from the first to last measurement. The time frame to obtain one sample is a few minutes of walking.

The MLE is sensitive to the degree to which the gait cycle tends to diverge from its average repeated pattern. It is typically computed with the Rosenstein algorithm applied to motion-tracking data recorded while the participant is walking. More specifically, the marker is placed on the participant's upper body close to the center-of-mass. MLE equal to zero indicates a neutrally stable dynamic with perfectly repeatable oscillation. Paradoxically, this is maladaptive. Very low values of MLE close to zero tend to be associated with motor disorders. Increasingly positive values of MLE correspond to higher tolerance for dynamic instability and are associated with a healthy gait pattern. There are also exceptions, not relevant to the present study, where very high instability corresponds to specific motor disorders.

研究点 (1)

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