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Six Months DHEA Treatment in Female Adrenal Failure

Not Applicable
Completed
Conditions
Adrenal Insufficiency
Registration Number
NCT00471900
Lead Sponsor
University of Aarhus
Brief Summary

DHEA is an adrenal deriven androgen precourser. The impact of DHEA substitution therapy in adrenal failure is unknown as well as the physiologically effects of DHEA is unknown. Effects of physiologically DHEA substitution is investigated in the model of female adrenal failure.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
10
Inclusion Criteria
  • Female,
  • Adrenal insuficiency,
  • Stable and safe anticonception,
  • Stable hydrocortison substituation treatment.
Exclusion Criteria
  • Neoplastic and thromboembolic disease,
  • Diabetes mellitus.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Quality of life parameteres, cardiovascular parameters, bodycomposition, exercise parameters, hormonal and serological parameters, fuel metabolisme.six months
Secondary Outcome Measures
NameTimeMethod
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