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临床试验/NCT06296108
NCT06296108已完成不适用

Risk Factors for Acute Kidney Injury in Patients Undergoing Total Joint Arthroplasty

Ankara University1 个研究点 分布在 1 个国家目标入组 911 人开始时间: 2022年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
911
试验地点
1
主要终点
Acute kidney injury in patients undergoing arthroplasty surgery

研究概览

简要总结

The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty.

详细描述

Aim: The primary aim of the current study is to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty. Considering that this patient group is mostly composed of advanced age and comorbid patients, the secondary aim of the study is to identify risky patients with predictable risk factors and to chart a way to make preoperative optimizations of the patients before developing postoperative complications.

Materials and Methods

Patients who underwent joint arthroplasty between 2015 and 2020 in Ankara University Faculty of Medicine, Department of Orthopedics and Traumatology were included. Within the scope of the study, patients' gender, age, weight, height, body mass index values, smoking, American Society of Anesthesiologist (ASA) score, Charlson-Comorbidity Index score (CCI), type of operation, duration of surgery, presence of intraoperative hypotension, anesthesia method , diabetes, hypertension, coronary artery disease, presence of congestive heart failure, presence of preoperative anemia, preoperative uric acid and albumin level, use of nephrotoxic agents in the perioperative period, basal creatinine and glomerular filtration rate (GFR) values, platelet suspension in the perioperative period, erythrocyte suspension, Amounts of fresh frozen plasma transfusions, postoperative creatinine at 24 hours - 48 hours - discharge, GFR values and Kidney Disesae Improving Global Outcomes (KDIGO) scores, length of hospital stay and length of stay in the intensive care unit were evaluated.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients aged above 18 years old undergoing arthroplasty surgery

排除标准

  • Known acute renal failure or chronic renal failure
  • Patients aged below 18 years old
  • Patients refusing to participate to the study

结局指标

主要结局

Acute kidney injury in patients undergoing arthroplasty surgery

时间窗: Retrospective between 2015-2020

To determine the incidence of acute kidney injury in patients undergoing arthroplasty surgery

次要结局

  • Risk factors causing acute kidney injury in patients undergoing arthroplasty surgery(Retrospective between 2015-2020)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sanem Cakar Turhan

Associate professor, MD

Ankara University

研究点 (1)

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