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Clinical Trials/NCT06296108
NCT06296108
Completed
Not Applicable

Risk Factors for Acute Kidney Injury in Patients Undergoing Total Joint Arthroplasty

Ankara University1 site in 1 country911 target enrollmentJune 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Acute Kidney Injury
Sponsor
Ankara University
Enrollment
911
Locations
1
Primary Endpoint
Acute kidney injury in patients undergoing arthroplasty surgery
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The authors aimed to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty.

Detailed Description

Aim: The primary aim of the current study is to determine the risk factors associated with postoperative acute kidney injury in patients undergoing total joint arthroplasty. Considering that this patient group is mostly composed of advanced age and comorbid patients, the secondary aim of the study is to identify risky patients with predictable risk factors and to chart a way to make preoperative optimizations of the patients before developing postoperative complications. Materials and Methods: Patients who underwent joint arthroplasty between 2015 and 2020 in Ankara University Faculty of Medicine, Department of Orthopedics and Traumatology were included. Within the scope of the study, patients' gender, age, weight, height, body mass index values, smoking, American Society of Anesthesiologist (ASA) score, Charlson-Comorbidity Index score (CCI), type of operation, duration of surgery, presence of intraoperative hypotension, anesthesia method , diabetes, hypertension, coronary artery disease, presence of congestive heart failure, presence of preoperative anemia, preoperative uric acid and albumin level, use of nephrotoxic agents in the perioperative period, basal creatinine and glomerular filtration rate (GFR) values, platelet suspension in the perioperative period, erythrocyte suspension, Amounts of fresh frozen plasma transfusions, postoperative creatinine at 24 hours - 48 hours - discharge, GFR values and Kidney Disesae Improving Global Outcomes (KDIGO) scores, length of hospital stay and length of stay in the intensive care unit were evaluated.

Registry
clinicaltrials.gov
Start Date
June 1, 2022
End Date
December 31, 2022
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sanem Cakar Turhan

Associate professor, MD

Ankara University

Eligibility Criteria

Inclusion Criteria

  • Patients aged above 18 years old undergoing arthroplasty surgery

Exclusion Criteria

  • Known acute renal failure or chronic renal failure
  • Patients aged below 18 years old
  • Patients refusing to participate to the study

Outcomes

Primary Outcomes

Acute kidney injury in patients undergoing arthroplasty surgery

Time Frame: Retrospective between 2015-2020

To determine the incidence of acute kidney injury in patients undergoing arthroplasty surgery

Secondary Outcomes

  • Risk factors causing acute kidney injury in patients undergoing arthroplasty surgery(Retrospective between 2015-2020)

Study Sites (1)

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