Biomarkers of wholegrain intake
- Conditions
- Changes in concentrations of biomarkers in response to changing wholegrain intakeNutritional, Metabolic, Endocrine
- Registration Number
- ISRCTN93493245
- Lead Sponsor
- Food Standards Agency (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 64
Males and females aged over 18 years
1. Allergies or intolerances to intervention foods
2. Individuals receiving any form of clinical treatment, and/or taking prescribed medications (clinical treatment will affect metabolic profile and/or bioavailability of nutrients from the intervention diet, potentially masking true dietary effects)
3. Individuals taking any form of dietary supplements (dietary supplements may affect metabolic profile and/or bioavailability of nutrients from the intervention diet, potentially masking true dietary effects)
4. Having dietary restrictions, apart from being a vegetarian (for example being on a detox or slimming diet) (some dietary restrictions could interfere with metabolic profile in response to wholegrain diet)
5. Planning to change dietary habits, increase physical activity, change body weight, move away from the study centre locality or to take a lengthy vacation during the time of the study (approximately 12 weeks)
6. Smokers (may affect metabolic profile through increased oxidative stress)
7. History of alcoholism or substance abuse (may affect compliance to dietary intervention and/or metabolic profile)
8. Body Mass Index < 20 kg/m2 or > 30 kg/m2 (very underweight or overweight individuals are likely to have disturbed metabolic profiles and metabolic response to diet)
9. Currently pregnant, planning pregnancy or having had a baby in the past 12 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method