Preparation Rich in Growth Factors (PRGF) Treatment for Osteoarthritis of the Knee

Phase 2

Completed

• Conditions: Osteoarthritis of the Knee
• Interventions: Biological: PRGF; Drug: placebo; Drug: hyaluronic acid

• Registration Number: NCT00728611
• Lead Sponsor: Meir Medical Center

Brief Summary

to evaluate the influence of PRGF treatment on patient suffering from OA knee

Detailed Description

Autologous platelet-secreted growth factors (GFs) may have therapeutic effects in osteoarthritis (OA) capsular joints via multiple mechanisms. Our aim is to examine the effect of a platelet-derived preparation rich in growth factors (PRGFs) in OA knee

Study Timeline

• Study Start: 2008-01
• Study First Submitted: 2008-08-03
• Study First Submitted QC: 2008-08-05
• Study First Posted: 2008-08-06
• Primary Completion: 2009-02
• Study Completion: 2009-03
• Status Verified: 2011-07
• Last Update Submitted: 2011-07-10
• Last Update Posted: 2011-07-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• age 40-75 years old
• diagnosed Oa of the knee more then 1 year
• no knee deformation

Exclusion Criteria

• mental of physical disabilities
• pregnancy
• deformities of the knee

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	PRGF	-
3	placebo	-
2	hyaluronic acid	-

Primary Outcome Measures

Name	Time	Method
Improvment of symptomes	1 year

Trial Locations

Locations (1)

Meir Medical Center; 🇮🇱 Kfar Saba, Israel