NCT04912362Unknown不适用
Effectiveness of YAG Laser Iridotomy in Preventing Peripheral Anterior Synechia After CO2 Laser-Assisted Sclerectomy Surgery in Primary Open Angle Glaucoma
Second Affiliated Hospital, School of Medicine, Zhejiang University1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2020年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Intraocular pressure
研究概览
简要总结
To investigate the effectiveness of YAG laser iridotomy in preventing peripheral anterior synechia after CO2 Laser-Assisted Sclerectomy Surgery and the long-term effect of reducing intraocular pressure
详细描述
Group A: YAG laser iridotomy was performed one week before operation, followed by CO2 Laser-Assisted Sclerectomy Surgery; Group B: only CO2 Laser-Assisted Sclerectomy Surgery; The patients were followed up for 1 year to observe and compare the difference of the incidence of peripheral anterior synechia and the effect of long-term intraocular pressure control between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Primary open angle glaucoma patients in Ophthalmic Center;
- •Topical use of hypotensive drugs in the treatment of poor or intolerable intraocular pressure control;
- •The patients were 18 to 50 years old, regardless of gender;
- •Class operation was performed;
- •Patients are able and willing to comply with the research guidance and may complete all visits required by the research;
- •Informed consent has been signed.
排除标准
- •Allergic to any perioperative medication in this study;
- •History of ocular trauma;
- •Any previous intraocular surgery;
- •Gonioscopy showed a narrow angle (Schaffer III or below);
- •Secondary glaucoma was diagnosed;
- •Optic atrophy caused by other reasons;
- •Severe complications such as rupture of posterior capsule and choroidal hemorrhage occurred during operation;
- •Patients with severe ocular complications after operation
- •The patient's history indicated that he had severe dysfunction of heart, lung, liver and kidney;
- •Women in pregnancy, lactation or planned pregnancy;
- •The researchers believe that the patient's condition may put the patient at significant risk, may confuse the results of the study, or may significantly interfere with the patient's participation in the study.
结局指标
主要结局
Intraocular pressure
时间窗: 1 year
Intraocular pressure
Peripheral anterior synechia
时间窗: 1 year
Incidence of peripheral anterior synechia
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
不适用
AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After PhacoemulsificationGlaucoma, Angle-ClosureNCT05332665Minia University15
Unknown
不适用
Laser Peripheral Iridotomy Plus Laser Peripheral Iridoplasty for Primary Angle ClosureGlaucoma, Angle-ClosureNCT02613013Sun Yat-sen University240
招募中
不适用
the Clinical Effect of Nd: YAG Laser Assisted Periodontal Initial Therapy in Patients With Moderate to Severe PeriodontitisPeriodontitisNCT06587334Second Affiliated Hospital, School of Medicine, Zhejiang University22
已完成
不适用
Lasers in Peri-implantitis TreatmentPeri-ImplantitisNCT05733234Aristotle University Of Thessaloniki20
已完成
1 期
Partial Posterior Hyaloidectomy in Macular SurgeryRetinal BreakRetinal DetachmentNCT01454466Samsung Medical Center50