AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification

• Conditions: Glaucoma, Angle-Closure
• Interventions: Device: AS-OCT; Procedure: YAG laser PI

• Registration Number: NCT05332665
• Lead Sponsor: Minia University

Brief Summary

Evaluation of the effect of phacoemulsification and YAG Laser peripheral iridotomy on the anterior chamber angle anatomic parameters in PACG eyes, using anterior segment optical coherence tomography (SS ASOCT) device

Detailed Description

The recent treatment of ACG is phacoemulsification in patients of acute attack with YAG laser iridotomy in the other eye.

The AS-OCT will be used for evaluation of the angle of the anterior chamber parameters in both eyes after phacoemulsification and YAG laser peripheral iridotomy.

Follow up of AS-OCT will be done 1,3,6 months after surgery and we will compare results in each eye and between both eyes.

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Study Timeline

• Study Start: 2022-01-11
• Study First Submitted: 2022-03-28
• Status Verified: 2022-04
• Study First Submitted QC: 2022-04-11
• Last Update Submitted: 2022-04-11
• Study First Posted: 2022-04-18
• Last Update Posted: 2022-04-18
• Primary Completion: 2022-12
• Study Completion: 2022-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• patients with acute attack of angle closure glaucoma in one eye.
• Patients fit for phacoemulsification

Exclusion Criteria

• 1- Patients with history of any intraocular surgery. 2- Patients with history of refractive surgery. 3- Patients with diabetic retinal vasculopathy or retinal detachment. 4- Patients with chronic angle closure glaucoma, open angle glaucoma or 2ry glaucoma

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Trabecular iris space area (TISA) 500	YAG laser PI	TISA 500 was measured as an area bounded anteriorly by the AOD 500, posteriorly by a line drawn from the scleral spur perpendicular to the plane of the inner scleral wall to the opposing iris, superiorly by the inner corneoscleral wall, and inferiorly by the iris surface
Angle opening distance (AOD)	AS-OCT	The AOD measured as perpendicular distance between anterior iris surface and point at trabecular meshwork at 500 μm anterior to the scleral spur
Trabecular iris space area (TISA) 500	AS-OCT	TISA 500 was measured as an area bounded anteriorly by the AOD 500, posteriorly by a line drawn from the scleral spur perpendicular to the plane of the inner scleral wall to the opposing iris, superiorly by the inner corneoscleral wall, and inferiorly by the iris surface
Angle opening distance (AOD)	YAG laser PI	The AOD measured as perpendicular distance between anterior iris surface and point at trabecular meshwork at 500 μm anterior to the scleral spur
Anterior chamber depth (ACD)	AS-OCT	The ACD was measured as the perpendicular distance from the corneal endothelium at the corneal apex to the anterior lens surface
Anterior chamber depth (ACD)	YAG laser PI	The ACD was measured as the perpendicular distance from the corneal endothelium at the corneal apex to the anterior lens surface

Primary Outcome Measures

Name	Time	Method
IOP	up to 6 months	mmhg

Secondary Outcome Measures

Name	Time	Method
Corneal endothelial count	up to 6 months	CD per mm2

Trial Locations

Locations (1)

mohamed Mahmoud; 🇪🇬 Minia, El Minia, Egypt