Anterior Segment- Optical Coherence Tomography as Early Biomarker in Diabetic Retinopathy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The measurements of corneal features in patients with type 2 diabetes mellitus, using anterior segment-optical coherence tomography
研究概览
简要总结
This study evaluates the corneal features using anterior segment - optical coherence tomography in patients affected by type 2 diabetes mellitus
详细描述
To investigate the potential role of anterior segment-optical coherence tomography (AS-OCT) in identifying the corneal changes (in particular in total corneal, epithelial and stromal thicknesses) in patients affected by type 2 diabetes mellitus, without signs of diabetic retinopathy at fundus examination.
The AS-OCT could represents a valid early biomarker in these patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 50 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age older than 50 years
- •diagnosis of previous type 2 diabetes mellitus
- •absence of signs of diabetic retinopathy
- •absence of previous ocular surgery, congenital eye disease, high myopia (>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
- •absence of significant lens opacities, low-quality OCT and OCT-A images
排除标准
- •age younger than 50 years
- •absence of previous diagnosis of type 2 diabetes mellitus
- •presence of signs of diabetic retinopathy
- •presence of previous ocular surgery, congenital eye disease, high myopia (>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
- •presence of significant lens opacities, low-quality OCT and OCT-A images.
结局指标
主要结局
The measurements of corneal features in patients with type 2 diabetes mellitus, using anterior segment-optical coherence tomography
时间窗: twelve months
The parameters analyzed by anterior segment-optical coherence tomography angiography were: total corneal, epithelial and stromal thicknesses
次要结局
未报告次要终点
研究者
Gilda Cennamo
Principal Investigator
Federico II University