Role of Anterior Segment Optical Coherence Tomography in Staging and Evaluation of Treatment Response in Infectious Keratitis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Infective Keratitis
- Sponsor
- Minia University
- Enrollment
- 23
- Locations
- 1
- Primary Endpoint
- width of lesion on optical coherence tomography
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
To evaluate the role of anterior segment optical coherence tomography in follow up of infectious keratitis and assessment of response to treatment.
Detailed Description
50 patients with proven infectious keratitis clinically will be included in the study. The following will be performed for all patients in initial visit and follow up: * Slit lamp examination and photography. * Visual acuity assessment. * Anterior segment optical coherence tomography. 1. The central corneal thickness (CCT) (extracted from pachymetry map), 2. Minimal corneal thickness (MCT) (extracted from pachymetry map) 3. Corneal thickness at the site of the lesion (CTL) (extracted from pachymetry map or the sum of STL+ CETL) 4. Stromal thickness at the center of the lesion (STL) stromal lesion (extracted from stromal map) 5. Corneal epithelial thickness over the stromal lesion (CETL) at the center of the lesion (extracted from epithelial map)
Investigators
Ahemd Abdelghany
Assistant professor
Minia University
Eligibility Criteria
Inclusion Criteria
- •Any case with infectious keratitis (any age) either received medical treatment or not, attending to our department will be included in the study.
Exclusion Criteria
- •Cases with healed infectious keratitis.
- •Cases presented from the start with severe corneal affection and melting.
Outcomes
Primary Outcomes
width of lesion on optical coherence tomography
Time Frame: 1 month
width of infiltration in microns
criteria of lesion on optical coherence tomography
Time Frame: 1 month
Localiztion, depth of infiltration area in microns