Comparing dimethyl sulfoxide solution versus topical tretinoin in cutaneous amyloidosis
Phase 3
Recruiting
- Conditions
- Primary localized cutaneous amyloidosis.Organ-limited amyloidosis
- Registration Number
- IRCT20181114041658N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Patients with clinical and pathological diagnosis of lichen and macular amyloidosis in trunk and lower limbs
bilateral amyloidosis
Exclusion Criteria
using other topical drugs in last four weeks
sensitivity to retinoids
hepatic disorders
breast feeding
pregnancy
no consent for photography
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Melanin. Timepoint: baseline and at the end of 4th, 12th, and 18th week of 20-week treatment period. Method of measurement: colorimetery (dermocatch).;Itching. Timepoint: baseline and at the end of 4th, 12th, and 18th week of 20-week treatment period. Method of measurement: itching scoring (0-10).;Erythema. Timepoint: baseline and at the end of 4th, 12th, and 18th week of 20-week treatment period. Method of measurement: colorimetery (dermocatch).
- Secondary Outcome Measures
Name Time Method