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Explanted Lung Tissues With Pulmonary Fibrosis

Recruiting
Conditions
Pulmonary Fibrosis
Registration Number
NCT00515567
Lead Sponsor
University of Chicago
Brief Summary

The goal of this study is to use the tissues from the explanted lungs in order to better study the cause of pulmonary fibrosis at a cellular level.

Detailed Description

Pulmonary Fibrosis involves scarring of the lung. Gradually, the air sacs of the lungs become replaced by fibrotic tissue. The most current thinking is that the fibrotic process is a reaction to tiny injury to the lung. When the scar forms, the tissue becomes thicker causing a permanent loss of the tissue's ability to carry oxygen into the bloodstream.

We need to obtain lung tissue from patients without pulmonary fibrosis and compare it to lung tissue from patients with pulmonary fibrosis.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
90
Inclusion Criteria
  • all patients awaiting lung transplant
Exclusion Criteria
  • all who will not give consent

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
assess fibroblasts and cytokines associated with pulmonary fibrosis12/2013
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

The University of Chicago

🇺🇸

Chicago, Illinois, United States

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