KCT0003367已完成未知
Effect of short-course radiotherapy followed by neoadjuvant Xelox (Capecitabine and Oxaliplatin) chemotherapy and total mesorectal excision in MRI defined high-risk rectal cancer: A phase II trial
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 31
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 19(Year) 至 80(Year)（—）
- 性别
- All
入选标准
- •1. High-risk patients of rectal cancer on pretreatment MRI using the following risk stratification system
- •? Location of the lower part of the tumor is measured below less than 10 cm on the anal verge and lower part of the tumor is located below the lower limit of the peritoneal reflection.
- •? If there is more than one, classify as a high risk group
- •? Positive CRM threatening:
- •? 5mm ? Extramural depth
- •? Positive EMVI.
- •? Positive Lateral pelvic LN metastasis
- •2. Between 19 and 80 years of age;
- •3. Satisfactory performance status: ECOG?2
- •4. American Society of Anesthesiologists (ASA) physical status classification system class I~III
- •5. Adequate hematologic function: white blood cell(WBC) counts=4,000/mm3, neutrophils counts = 2,000/mm3, platelet counts = 1000,000/µL, hemoglobin = 9g/L;
- •6. Adequate renal function: creatinine = 1.5×upper normal limit
排除标准
- •1. The evidenc of relapse of distant metastasis
- •2. Receiving treatment of other anti-cancer drug or methods
- •3. Patients have low compliance and are not able to complete the entire trial
- •4. Presence of uncontrolled life-threatening diseases
- •5. cT4 with infiltration of anterior organ on pretreatment MRI
- •6. cT4 with infiltration of internal or external anal sphincter on pretreatment MRI
研究者
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